Buffalo Bills 2025 Schedule
AFC EAST
| Matchup | Result/Time | ||
| Wk 1 | Sun 9/7 | 
Baltimore Ravens
Ravens
| W, 41-40 |
| Wk 2 | Sun 9/14 | @ 
New York Jets
Jets
| W, 30-10 |
| Wk 3 | Thu 9/18 | 
Miami Dolphins
Dolphins
| W, 31-21 |
| Wk 4 | Sun 9/28 | 
New Orleans Saints
Saints
| W, 31-19 |
| Wk 5 | Sun 10/5 | 
New England Patriots
Patriots
| L, 23-20 |
| Wk 6 | Mon 10/13 | @ 
Atlanta Falcons
Falcons
| L, 24-14 |
| Wk 8 | Sun 10/26 | @ 
Carolina Panthers
Panthers
| W, 40-9 |
| Wk 9 | Sun 11/2 | 
Kansas City Chiefs
Chiefs
| W, 28-21 |
| Wk 10 | Sun 11/9 | @
Miami Dolphins
Dolphins
| L, 30-13 |
| Wk 11 | Sun 11/16 | 
Tampa Bay Buccaneers
Buccaneers
| W, 44-32 |
| Wk 12 | Thu 11/20 | @ 
Houston Texans
Texans
| L, 23-19 |
| Wk 13 | Sun 11/30 | @ 
Pittsburgh Steelers
Steelers
| W, 26-7 |
| Wk 14 | Sun 12/7 | 
Cincinnati Bengals
Bengals
| 1:00 PM |
| Wk 15 | Sun 12/14 | @
New England Patriots
Patriots
| 1:00 PM |
| Wk 16 | Sun 12/21 | @ 
Cleveland Browns
Browns
| 1:00 PM |
| Wk 17 | Sun 12/28 | 
Philadelphia Eagles
Eagles
| 4:25 PM |
| Wk 18 | Sun 1/4 |
New York Jets
Jets
| 12:00 AM |