Indianapolis Colts 2025 Schedule
AFC SOUTH
| Matchup | Result/Time | ||
| Wk 1 | Sun 9/7 | 
Miami Dolphins
Dolphins
| W, 33-8 |
| Wk 2 | Sun 9/14 | 
Denver Broncos
Broncos
| W, 29-28 |
| Wk 3 | Sun 9/21 | @ 
Tennessee Titans
Titans
| W, 41-20 |
| Wk 4 | Sun 9/28 | @ 
Los Angeles Rams
Rams
| L, 27-20 |
| Wk 5 | Sun 10/5 | 
Las Vegas Raiders
Raiders
| W, 40-6 |
| Wk 6 | Sun 10/12 | 
Arizona Cardinals
Cardinals
| W, 31-27 |
| Wk 7 | Sun 10/19 | @ 
Los Angeles Chargers
Chargers
| W, 38-24 |
| Wk 8 | Sun 10/26 |
Tennessee Titans
Titans
| W, 38-14 |
| Wk 9 | Sun 11/2 | @ 
Pittsburgh Steelers
Steelers
| L, 27-20 |
| Wk 10 | Sun 11/9 | 
Atlanta Falcons
Falcons
| W, 31-25 |
| Wk 12 | Sun 11/23 | @ 
Kansas City Chiefs
Chiefs
| L, 23-20 |
| Wk 13 | Sun 11/30 | 
Houston Texans
Texans
| L, 20-16 |
| Wk 14 | Sun 12/7 | @ 
Jacksonville Jaguars
Jaguars
| 1:00 PM |
| Wk 15 | Sun 12/14 | @ 
Seattle Seahawks
Seahawks
| 4:25 PM |
| Wk 16 | Mon 12/22 | 
San Francisco 49ers
49ers
| 8:15 PM |
| Wk 17 | Sun 12/28 |
Jacksonville Jaguars
Jaguars
| 1:00 PM |
| Wk 18 | Sun 1/4 | @
Houston Texans
Texans
| 12:00 AM |