East Carolina Pirates 2025 Schedule
AMERICAN-ATHLETIC
| Matchup | Result/Time | ||
| Wk 1 | Thu 8/28 | @ 
North Carolina State
North Carolina St...
| L, 24-17 |
| Wk 2 | Sat 9/6 | Campbell Campbell | W, 56-3 |
| Wk 3 | Sat 9/13 | @ 
Coastal Carolina
Coastal Carolina
| W, 38-0 |
| Wk 4 | Sat 9/20 | 
BYU
BYU
| L, 34-13 |
| Wk 5 | Thu 9/25 | 
Army
Army
| W, 28-6 |
| Wk 7 | Thu 10/9 | @ 
Tulane
Tulane
| L, 26-19 |
| Wk 8 | Thu 10/16 | 
Tulsa
Tulsa
| W, 41-27 |
| Wk 10 | Sat 11/1 | @ 
Temple
Temple
| W, 45-14 |
| Wk 11 | Sat 11/8 | 
Charlotte
Charlotte
| W, 48-22 |
| Wk 12 | Sat 11/15 | 
Memphis
Memphis
| W, 31-27 |
| Wk 13 | Sat 11/22 | @ 
UTSA
UTSA
| L, 58-24 |
| Wk 14 | Sat 11/29 | @ 
Florida Atlantic
Florida Atlantic
| W, 42-3 |