Louisville Cardinals 2024 Schedule
| ACC |
| Matchup | Result/Time | ||
| Week 1 | Sat Aug 31, 2024 | Austin Peay | W, 62-0 |
| Week 2 | Sat Sep 7, 2024 |  Jacksonville State | W, 49-14 |
| Week 4 | Sat Sep 21, 2024 |  Georgia Tech | W, 31-19 |
| Week 5 | Sat Sep 28, 2024 | @  Notre Dame | L, 31-24 |
| Week 6 | Sat Oct 5, 2024 |  SMU | L, 34-27 |
| Week 7 | Sat Oct 12, 2024 | @  Virginia | W, 24-20 |
| Week 8 | Sat Oct 19, 2024 |  Miami | L, 52-45 |
| Week 9 | Fri Oct 25, 2024 | @  Boston College | W, 31-27 |
| Week 10 | Sat Nov 2, 2024 | @  Clemson | W, 33-21 |
| Week 12 | Sat Nov 16, 2024 | @  Stanford | L, 38-35 |
| Week 13 | Sat Nov 23, 2024 |  Pittsburgh | W, 37-9 |
| Week 14 | Sat Nov 30, 2024 | @  Kentucky | W, 41-14 |