SMU Mustangs 2025 Schedule
ACC
| Matchup | Result/Time | ||
| Wk 1 | Sat 8/30 | East Texas A&M East Texas A&M | W, 42-13 |
| Wk 2 | Sat 9/6 | 
Baylor
Baylor
| L, 48-45 |
| Wk 3 | Sat 9/13 | @ 
Missouri State
Missouri State
| W, 28-10 |
| Wk 4 | Sat 9/20 | @ 
TCU
TCU
| L, 35-24 |
| Wk 6 | Sat 10/4 | 
Syracuse
Syracuse
| W, 31-18 |
| Wk 7 | Sat 10/11 | 
Stanford
Stanford
| W, 34-10 |
| Wk 8 | Sat 10/18 | @ 
Clemson
Clemson
| W, 35-24 |
| Wk 9 | Sat 10/25 | @ 
Wake Forest
Wake Forest
| L, 13-12 |
| Wk 10 | Sat 11/1 | 
Miami
Miami
| W, 26-20 |
| Wk 11 | Sat 11/8 | @ 
Boston College
Boston College
| W, 45-13 |
| Wk 13 | Sat 11/22 | 
Louisville
Louisville
| W, 38-6 |
| Wk 14 | Sat 11/29 | @ 
California
California
| L, 38-35 |