Pittsburgh Panthers 2025 Schedule
ACC
| Matchup | Result/Time | ||
| Wk 1 | Sat 8/30 | Duquesne DUQ | W, 61-9 |
| Wk 2 | Sat 9/6 | 
Central Michigan
CMICH
| W, 45-17 |
| Wk 3 | Sat 9/13 | @ 
West Virginia
WVIR
| L, 31-24 |
| Wk 5 | Sat 9/27 | 
Louisville
LOU
| L, 34-27 |
| Wk 6 | Sat 10/4 | 
Boston College
BOSCOL
| W, 48-7 |
| Wk 7 | Sat 10/11 | @ 
Florida State
FLST
| W, 34-31 |
| Wk 8 | Sat 10/18 | @ 
Syracuse
SYRA
| W, 30-13 |
| Wk 9 | Sat 10/25 | 
North Carolina State
NCST
| W, 53-34 |
| Wk 10 | Sat 11/1 | @ 
Stanford
STAN
| W, 35-20 |
| Wk 12 | Sat 11/15 | 
Notre Dame
ND
| L, 37-15 |
| Wk 13 | Sat 11/22 | @ 
Georgia Tech
GTECH
| W, 42-28 |
| Wk 14 | Sat 11/29 | 
Miami
MIA
| L, 38-7 |
| Matchup - Postseason | Result/Time | ||
| Wk 99 | Sat 12/27 | @ 
East Carolina
ECAR
| L, 23-17 |