Purdue Boilermakers 2025 Schedule
BIG-TEN
| Matchup | Result/Time | ||
| Wk 1 | Sat 8/30 | 
Ball State
Ball State
| W, 31-0 |
| Wk 2 | Sat 9/6 | Southern Illinois Southern Illinois | W, 34-17 |
| Wk 3 | Sat 9/13 | 
USC
USC
| L, 33-17 |
| Wk 4 | Sat 9/20 | @ 
Notre Dame
Notre Dame
| L, 56-30 |
| Wk 6 | Sat 10/4 | 
Illinois
Illinois
| L, 43-27 |
| Wk 7 | Sat 10/11 | @ 
Minnesota
Minnesota
| L, 27-20 |
| Wk 8 | Sat 10/18 | @ 
Northwestern
Northwestern
| L, 19-0 |
| Wk 9 | Sat 10/25 | 
Rutgers
Rutgers
| L, 27-24 |
| Wk 10 | Sat 11/1 | @ 
Michigan
Michigan
| L, 21-16 |
| Wk 11 | Sat 11/8 | 
Ohio State
Ohio State
| L, 34-10 |
| Wk 12 | Sat 11/15 | @ 
Washington
Washington
| L, 49-13 |
| Wk 14 | Fri 11/28 | 
Indiana
Indiana
| L, 56-3 |