Penn State Nittany Lions 2025 Schedule
BIG-TEN
| Matchup | Result/Time | ||
| Wk 1 | Sat 8/30 | 
Nevada
Nevada
| W, 46-11 |
| Wk 2 | Sat 9/6 | 
Florida International
Florida Internati...
| W, 34-0 |
| Wk 3 | Sat 9/13 | Villanova Villanova | W, 52-6 |
| Wk 5 | Sat 9/27 | 
Oregon
Oregon
| L, 30-24 |
| Wk 6 | Sat 10/4 | @ 
UCLA
UCLA
| L, 42-37 |
| Wk 7 | Sat 10/11 | 
Northwestern
Northwestern
| L, 22-21 |
| Wk 8 | Sat 10/18 | @ 
Iowa
Iowa
| L, 25-24 |
| Wk 10 | Sat 11/1 | @ 
Ohio State
Ohio State
| L, 38-14 |
| Wk 11 | Sat 11/8 | 
Indiana
Indiana
| L, 27-24 |
| Wk 12 | Sat 11/15 | @ 
Michigan State
Michigan State
| W, 28-10 |
| Wk 13 | Sat 11/22 | 
Nebraska
Nebraska
| W, 37-10 |
| Wk 14 | Sat 11/29 | @ 
Rutgers
Rutgers
| W, 40-36 |
| Matchup - Postseason | Result/Time | ||
| Wk 99 | Sat 12/27 | @ 
Clemson
Clemson
| W, 22-10 |