USC Trojans 2025 Schedule
BIG-TEN
| Matchup | Result/Time | ||
| Wk 1 | Sat 8/30 | 
Missouri State
Missouri State
| W, 73-13 |
| Wk 2 | Sat 9/6 | 
Georgia Southern
Georgia Southern
| W, 59-20 |
| Wk 3 | Sat 9/13 | @ 
Purdue
Purdue
| W, 33-17 |
| Wk 4 | Sat 9/20 | 
Michigan State
Michigan State
| W, 45-31 |
| Wk 5 | Sat 9/27 | @ 
Illinois
Illinois
| L, 34-32 |
| Wk 7 | Sat 10/11 | 
Michigan
Michigan
| W, 31-13 |
| Wk 8 | Sat 10/18 | @ 
Notre Dame
Notre Dame
| L, 34-24 |
| Wk 10 | Sat 11/1 | @ 
Nebraska
Nebraska
| W, 21-17 |
| Wk 11 | Fri 11/7 | 
Northwestern
Northwestern
| W, 38-17 |
| Wk 12 | Sat 11/15 | 
Iowa
Iowa
| W, 26-21 |
| Wk 13 | Sat 11/22 | @ 
Oregon
Oregon
| L, 42-27 |
| Wk 14 | Sat 11/29 | 
UCLA
UCLA
| W, 29-10 |