Oklahoma State Cowboys 2025 Schedule
BIG-12
| Matchup | Result/Time | ||
| Wk 1 | Thu 8/28 | UT Martin UT Martin | W, 27-7 |
| Wk 2 | Sat 9/6 | @ 
Oregon
Oregon
| L, 69-3 |
| Wk 4 | Fri 9/19 | 
Tulsa
Tulsa
| L, 19-12 |
| Wk 5 | Sat 9/27 | 
Baylor
Baylor
| L, 45-27 |
| Wk 6 | Sat 10/4 | @ 
Arizona
Arizona
| L, 41-13 |
| Wk 7 | Sat 10/11 | 
Houston
Houston
| L, 39-17 |
| Wk 8 | Sat 10/18 | 
Cincinnati
Cincinnati
| L, 49-17 |
| Wk 9 | Sat 10/25 | @ 
Texas Tech
Texas Tech
| L, 42-0 |
| Wk 10 | Sat 11/1 | @ 
Kansas
Kansas
| L, 38-21 |
| Wk 12 | Sat 11/15 | 
Kansas State
Kansas State
| L, 14-6 |
| Wk 13 | Sat 11/22 | @ 
UCF
UCF
| L, 17-14 |
| Wk 14 | Sat 11/29 | 
Iowa State
Iowa State
| L, 20-13 |