Houston Cougars 2025 Schedule
BIG-12
| Matchup | Result/Time | ||
| Wk 1 | Thu 8/28 | Stephen F. Austin Stephen F. Austin | W, 27-0 |
| Wk 2 | Sat 9/6 | @ 
Rice
Rice
| W, 35-9 |
| Wk 3 | Fri 9/12 | 
Colorado
Colorado
| W, 36-20 |
| Wk 5 | Fri 9/26 | @ 
Oregon State
Oregon State
| W, 27-24 |
| Wk 6 | Sat 10/4 | 
Texas Tech
Texas Tech
| L, 35-11 |
| Wk 7 | Sat 10/11 | @ 
Oklahoma State
Oklahoma State
| W, 39-17 |
| Wk 8 | Sat 10/18 | 
Arizona
Arizona
| W, 31-28 |
| Wk 9 | Sat 10/25 | @ 
Arizona State
Arizona State
| W, 24-16 |
| Wk 10 | Sat 11/1 | 
West Virginia
West Virginia
| L, 45-35 |
| Wk 11 | Fri 11/7 | @ 
UCF
UCF
| W, 30-27 |
| Wk 13 | Sat 11/22 | 
TCU
TCU
| L, 17-14 |
| Wk 14 | Sat 11/29 | @ 
Baylor
Baylor
| W, 31-24 |