San Francisco 49ers 2024 Schedule
| NFC WEST |
| Matchup - Preseason | Time | ||
| Week 1 | Sat Aug 10, 2024 | @  Tennessee Titans | Final |
| Week 2 | Sun Aug 18, 2024 |  New Orleans Saints | Final |
| Week 3 | Fri Aug 23, 2024 | @  Las Vegas Raiders | Final |
| Matchup | Time | ||
| Week 1 | Mon Sep 9, 2024 |  New York Jets | Final |
| Week 2 | Sun Sep 15, 2024 | @  Minnesota Vikings | Final |
| Week 3 | Sun Sep 22, 2024 | @  Los Angeles Rams | Final |
| Week 4 | Sun Sep 29, 2024 |  New England Patriots | Final |
| Week 5 | Sun Oct 6, 2024 |  Arizona Cardinals | Final |
| Week 6 | Thu Oct 10, 2024 | @  Seattle Seahawks | Final |
| Week 7 | Sun Oct 20, 2024 |  Kansas City Chiefs | 4:25 PM |
| Week 8 | Sun Oct 27, 2024 |  Dallas Cowboys | 8:20 PM |
| Week 10 | Sun Nov 10, 2024 | @  Tampa Bay Buccaneers | 1:00 PM |
| Week 11 | Sun Nov 17, 2024 | Seattle Seahawks | 4:05 PM |
| Week 12 | Sun Nov 24, 2024 | @  Green Bay Packers | 4:25 PM |
| Week 13 | Sun Dec 1, 2024 | @  Buffalo Bills | 8:20 PM |
| Week 14 | Sun Dec 8, 2024 |  Chicago Bears | 4:25 PM |
| Week 15 | Thu Dec 12, 2024 | Los Angeles Rams | 8:15 PM |
| Week 16 | Sun Dec 22, 2024 | @  Miami Dolphins | 4:25 PM |
| Week 17 | Mon Dec 30, 2024 |  Detroit Lions | 8:15 PM |
| Week 18 | Sun Jan 5, 2025 | @ Arizona Cardinals | 12:00 AM |