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Christian McCaffrey  • RB  •  49ers

Christian McCaffrey to Play in Week 15

Per the team, San Francisco 49ers running back Christian McCaffrey (back, illness) will be active for Week 15's home matchup with the Tennessee Titans. Fresh off a bye week, the fantasy stalwart gave owners a scare after coming down with an illness. A late-week back issue offered no solace, but it appears that McCaffrey will be out there despite just one full practice this week. Fantasy managers can exhibit no worries slotting him into their lineups, as it doesn't appear he's in any danger of playing less than his typical allotment of snaps. McCaffrey is an elite RB1 option, and, officially, RotoBaller's PPR RB1 in this week's rankings.
1 hour ago   
Jauan Jennings  • WR  •  49ers

Jauan Jennings Set Up for Success Against Titans

San Francisco 49ers wide receiver Jauan Jennings should benefit from a favorable matchup against the Tennessee Titans in Week 15. While the Titans' pass defense has been better than their run defense, they've still allowed the sixth-most receiving yards and seventh-most fantasy points to opposing wide receivers in 2025. Jennings has been one of the more dependable targets in San Francisco, scoring a touchdown in four of his last five games. During that span, he ranks as the overall WR20 in PPR leagues. He'll face competition from Christian McCaffrey and lose some targets to George Kittle, but there's no denying that Jennings is the best true wide receiver on the 49ers, especially with Ricky Pearsall catching just five passes over his last three games. Jennings is the overall WR23 in RotoBaller's latest fantasy rankings, and he should be started in all leagues.
6 hours ago   
Christian McCaffrey  • RB  •  49ers

Christian McCaffrey Trending Toward Playing in Week 15

San Francisco 49ers running back Christian McCaffrey (back) "should be good to go" for Sunday's Week 15 contest against the Tennessee Titans, according to Ian Rapoport of NFL.com. McCaffrey entered the weekend without an injury designation, but he was added to the injury report on Saturday with a questionable tag. In the end, the star running back is expected to suit up in a very favorable matchup against a struggling Titans run defense that has allowed the third-most rushing touchdowns to opposing running backs in 2025. If he's near 100 percent, McCaffrey will rank as a high-end RB1 in fantasy football.
8 hours ago   
Brock Purdy  • QB  •  49ers

Brock Purdy Should Have Success in Week 15

San Francisco 49ers quarterback Brock Purdy is looking to bounce back after a few lackluster games. Purdy has been held to under 200 passing yards with three interceptions over his last two contests. The 25-year-old hasn't been an ideal fantasy option lately, but could be on the upswing. Purdy heads into a favorable matchup against the Tennessee Titans in Week 15. A defense that gave up over 350 passing yards to Shedeur Sanders last week. The Titans are currently allowing the eighth-most fantasy points to quarterbacks this season. All signs are pointing to Purdy having a bounce-back performance this weekend. He should be put in the QB1 conversation for this weekend.
21 hours ago   
Brandon Aiyuk  • WR  •  49ers

Brandon Aiyuk Placed on Reserve/Left Squad List, Out for the Season

San Francisco 49ers wide receiver Brandon Aiyuk (knee) was placed on the reserve/left squad list on Saturday. This move will make Aiyuk ineligible to return and will end his season. Aiyuk has been out all season while recovering from ACL and MCL tears in his right knee, which he suffered during the 2024 season. All signs are pointing to the two sides splitting apart this offseason. The 27-year-old should draw interest on the free agent market, but he's likely taken his last snap in San Francisco. Aiyuk is worth stashing in dynasty formats, but it's unclear how this knee injury is going to impact his performance on the field in the future. He can safely be dropped in all redraft formats with his 2025 season being officially over.
21 hours ago   
Christian McCaffrey  • RB  •  49ers

Christian McCaffrey Expected to Play in Week 15

San Francisco 49ers running back Christian McCaffrey (back) popped up on the injury report on Saturday due to a back issue. According to Adam Schefter, McCaffrey is expected to suit up for the Week 15 matchup against the Tennessee Titans. This issue doesn't appear to be severe enough to keep McCaffrey on the sideline. If he suffers a setback, Brian Robinson Jr. and Isaac Guerendo would likely split up a majority of the snaps in the backfield. Fantasy managers should expect McCaffrey out there on Sunday, but there probably won't be official word until closer to kickoff. The 49ers don't play until 4:25 pm ET, so his official announcement might not be made until sometime in the afternoon.
22 hours ago   
Christian McCaffrey  • RB  •  49ers

Christian McCaffrey Questionable for Sunday With Back Injury

San Francisco 49ers running back Christian McCaffrey (back) has been added back to the Week 15 injury report and is now listed as questionable for Sunday's game against the Tennessee Titans due to a back injury, according to Matt Barrows of The Athletic. It's a concerning sign to see the superstar back be added to the Week 15 injury report this late in the week, so his status needs to be monitored up until gametime on Sunday. McCaffrey has handled the biggest workload in the league this season with 322 touches in 13 games and has arguably been the best player in fantasy football. Fantasy managers should rush to pick up Brian Robinson Jr. if he is available, as he would be in line for a workhorse role on Sunday in a solid matchup against the Titans if McCaffrey ends up being ruled out.
23 hours ago   
Brandon Aiyuk  • WR  •  49ers

49ers' "Optimism Has Run Out" on Brandon Aiyuk

The Athletic's Dianna Russini reports that the San Francisco 49ers' "optimism seems to have run out" that wide receiver Brandon Aiyuk (knee) would report to the team ready to practice. Aiyuk has yet to play this season as he recovers from a serious knee injury that ended his 2024 season in Week 7. The team voided guaranteed money on Aiyuk's contract for the 2026 season, which seems to be a sticking point for the wide receiver as well. It's not entirely clear if Aiyuk will ever play another game for San Francisco, but Russini reports that she "expect(s) a resolution sooner rather than later." In Aiyuk's last fully healthy season, he recorded 75 receptions for 1,342 yards and seven touchdowns on 105 targets across 16 games in 2023. If Aiyuk's time in San Francisco is coming to a close, he would surely have interest from teams on the open market.
Yesterday   
Demarcus Robinson  • WR  •  49ers

Demarcus Robinson A Distant Third On Depth Chart

San Francisco 49ers wide receiver Demarcus Robinson appears to be holding onto his spot on the depth chart behind Jauan Jennings and Ricky Pearsall. Robinson drew more snaps than Kendrick Bourne for the third straight game in Week 13, leading into the 49ers' bye. The extra time on the field did not amount to any significant production, however, and Robinson finished the game with one carry for a six-yard gain. Despite injuries to Jennings, Pearsall, and George Kittle earlier this season, Robinson was unable to establish a greater role for himself. On the season, he has 13 receptions for 163 yards on 24 targets. He is unlikely to make an impact in Sunday's matchup against the Titans. Despite a forgiving matchup against a bottom-tier defense, Robinson can be left off of fantasy football rosters entirely in Week 15.
Yesterday   
Eddy Piñeiro  • K  •  49ers

Eddy Pineiro Back In Action In Week 15

San Francisco 49ers kicker Eddy Pineiro (hamstring) appears to have recovered from the hamstring injury that sidelined him in Weeks 12 and 13. Pineiro was a full participant in each practice this week, and the 49ers cut backup kicker Matt Gay, indicating that Pineiro will be on the field in Week 15 against the Titans. Pineiro is a decent option for the first round of the fantasy football playoffs, though it is unlikely to be a ceiling game for the 30-year-old, for the simple fact that Tennessee's defense is among the worst in the league. The Titans are so prone to giving up touchdowns (40 allowed, tied for third-most in the NFL) that it may limit Pinieiro's chances to deliver fantasy points via field goals. Still, Pineiro can be trusted to make the most of the opportunities he does see (22-for-22 on field goal attempts).
Yesterday   
George Kittle  • TE  •  49ers

George Kittle In Contention For Another Top-12 Finish

San Francisco 49ers tight end George Kittle has finished in TE1 territory in five of his eight games played in 2025. After a five-week stint on injured reserve, Kittle put up an unprecedented goose egg in his first game back. But in Weeks 8 through 13, he ranked fourth in targets and second in both receptions and yardage among tight ends. In the 49ers' last four games, Kittle led the team with 30 targets and averaged 6.3 receptions and 74 yards per game. Kittle should remain one of Brock Purdy's top targets, along with Jauan Jennings and Christian McCaffrey, when the Niners host the Titans on Sunday. Tennessee hasn't been particularly vulnerable to tight ends in 2025, but was gashed for 114 yards and a touchdown by Harold Fannin Jr. last week. Kittle is a safe start for Week 15.
Yesterday   
Ricky Pearsall  • WR  •  49ers

Ricky Pearsall Hard To Trust In Week 15

San Francisco 49ers wide receiver Ricky Pearsall will be hard to trust this week, given his recent production. In the three games since returning from a PCL injury, Pearsall has just five receptions total for 20 yards. Before the injury, Pearsall averaged five catches and 81.8 yards per game while George Kittle and Jauan Jennings were limited or out due to injuries of their own. Now that both are back to full health, Pearsall seems to be the odd man out. The former Florida Gator has a good matchup with the Titans, who have allowed the ninth-most fantasy points to wide receivers, but his post-injury output makes him a risky bet to suddenly jump ahead of Kittle, Jennings, and Christian McCaffrey in the pecking order of pass-catchers. Pearsall projects as a WR5 in Week 15 and is probably better left on the bench on Sunday.
Yesterday   
Jauan Jennings  • WR  •  49ers

Jauan Jennings Has An Inviting Matchup In Week 15

San Francisco 49ers wide receiver Jauan Jennings will get a chance to build on his recent bump in productivity when the team hosts the Titans in Week 15. Jennings is riding a seven-game streak with at least four receptions and has caught a touchdown in four of the 49ers' last games. It should be noted that in that span, he averaged just 49.2 receiving yards per game. He will have a chance to do more damage against a Titans secondary that has allowed at least 76 receiving yards plus a touchdown to their opponents' leading receivers in each of their last four games. Jennings has seemingly been unaffected by Ricky Pearsall's return to action and is consistently among one of Brock Purdy's favorite targets, alongside George Kittle and Christian McCaffrey. Jennings projects as a WR2 in Week 15, making him a viable starter as the fantasy football playoffs get underway.
Yesterday   
Brian Robinson Jr.  • RB  •  49ers

Brian Robinson Jr. Unlikely To Factor Into Week 15

San Francisco 49ers running back Brian Robinson Jr. is off the fantasy radar for Week 15, despite an inviting matchup against the Tennessee Titans and a recent uptick in opportunities. Over the 49ers' last five games, Robinson is averaging 7.2 carries and 36.8 rushing yards per game, compared to his season-long averages of 5.5 and 25.2, respectively. Without the touchdowns like those he scored in Weeks 9 and 10, Robinson is a non-factor in fantasy football. Despite the lack of production, Robinson is a must-stash handcuff heading into the fantasy football playoffs. Should Christian McCaffrey (illness) ever be brought down by injury, Robinson would immediately step into a bellcow role. For Week 15, Robinson should remain on the bench.
Yesterday   
Christian McCaffrey  • RB  •  49ers

Christian McCaffrey Has Juicy Matchup In Week 15

San Francisco 49ers running back Christian McCaffrey (illness) gave fantasy football managers a scare when he popped up on the team's injury report earlier this week, raising concern over his availability in Week 15. Fortunately, McCaffrey got in a full session on Friday and has been cleared for Sunday. CMC will be able to take advantage of an inviting matchup against the Titans, who have given up 4.49 yards per carry and 17 total touchdowns to running backs in 2025. San Francisco's offense has run through McCaffrey this season, who not only has the third-most rushing attempts in the NFL (237) but also ranks fifth in receptions (85). McCaffrey has finished as a top-12 running back in 12 of the 49ers' 13 games, and he will be in the mix again in the first round of the fantasy football playoffs.
Yesterday   
Brock Purdy  • QB  •  49ers

Brock Purdy Back In QB1 Mix

San Francisco 49ers quarterback Brock Purdy is back in the QB1 conversation in Week 15. On Sunday, Purdy and the Niners face the Titans, who have allowed 22.4 fantasy points per game to opposing quarterbacks in 2025. Last week, Tennessee got torched by rookie Shedeur Sanders to the tune of 364 yards and three touchdowns through the air, and another 29 yards with an additional score on the ground. The Titans have given up multiple passing touchdowns in six of their last seven games and averaged 265 passing yards allowed during the same stretch. This is promising for Purdy, who has averaged just 187 passing yards per game since returning in Week 11 from a six-game absence managing turf toe. Purdy is a solid option in two-QB formats and is a good pivot from similar quarterbacks with more imposing matchups in Week 15.
Yesterday   
Christian McCaffrey  • RB  •  49ers

Christian McCaffrey Ready to Roll in Week 15

San Francisco 49ers running back Christian McCaffrey (illness) was a full-go in practice on Friday and was removed from the Week 15 injury report, according to Cam Inman of the Bay Area News Group. McCaffrey is fully expected to play on Sunday against the visiting Tennessee Titans after he came down with an illness this week and was limited in practice on Thursday. CMC is an absolute must-start in Week 15 against the Titans, a team that allows 122.5 rushing yards per game. The 29-year-old comes into Week 15 action as the RB2 in half-PPR points on the year, thanks to 849 rushing yards and eight touchdowns on 237 carries. McCaffrey hasn't been that great on the ground, but where he excels is as a pass-catcher, as he leads all backs in catches (85), targets (107), receiving yards (806), and touchdowns (five), and it's not even close.
Yesterday   
Christian McCaffrey  • RB  •  49ers

Christian McCaffrey Limited Thursday Due to Illness

San Francisco 49ers running back Christian McCaffrey (illness) was a limited participant during practice on Thursday. This was an improvement in status for McCaffrey, who missed practice entirely on Wednesday. He's trending in the right direction to play against the Tennessee Titans in Week 15, but managers should check back on Friday for additional confirmation on his status. If he's able to practice in full, he could avoid any sort of injury designation heading into the weekend. However, if he remains limited, the 49ers may list him as questionable. With that being said, the fact that McCaffrey was able to get on the field in some capacity on Thursday bodes well for his Week 15 availability. If active, he'll rank as a high-end RB1 against the Titans, who have allowed the 10th-most fantasy points to running backs in 2025.
2 days ago   
Jauan Jennings  • WR  •  49ers

Jauan Jennings Surges into Fantasy Playoffs

After a slow start to the 2025 season, San Francisco 49ers wide receiver Jauan Jennings has proved himself as a must-start receiver moving into the fantasy playoffs. Jennings has caught a touchdown in four of his last five starts and has averaged 13.9 PPR fantasy points per game since Week 9. His hot streak has gotten him back to his WR1 role in San Francisco, ahead of Ricky Pearsall and Brandon Aiyuk. With Aiyuk (knee) unlikely to play in 2025, Jennings has no reason to slow down. He faces the Tennessee Titans in Week 15, who have allowed the sixth-most receiving yards to wide receivers in 2025, and struggled to maintain Browns rookie quarterback Shedeur Sanders in the snow in Week 14. Fantasy managers can fully trust Jennings as a starting option in the fantasy playoffs, as he looks to extend his touchdown streak following the bye.
3 days ago   
Eddy Piñeiro  • K  •  49ers

Eddy Pineiro Expected to Return in Week 15

San Francisco 49ers kicker Eddy Pineiro (hamstring) practiced in full on Wednesday and is expected to return in Week 15. Pineiro has missed the previous two games due to a hamstring injury. Still, with extra time to recover from the bye week, Pineiro is expected to return to face the Tennessee Titans. The sixth-year veteran is having a career season, making all 22 field goal attempts this season, and ranking as the 6th-ranked kicker on a per-game basis. With the 49ers listed as big favorites and one of the highest implied totals of the weekend, Pineiro is a sneaky option as a kicker this week for fantasy purposes.
3 days ago   
LEGEND