San Francisco 49ers News

San Francisco 49ers left tackle Trent Williams (ankle) did not practice on Wednesday. Williams has been receiving rest days for much of the season and his ankle has been bothering him for a while. However, the 49ers generally list Williams with his injury and as resting so his situation is worth monitoring moving forward. Williams is a rare non-skill position player that has a lot of fantasy relevance. Williams is simply a huge piece of the 49ers' offense. When he is in the lineup, both the running and passing games click. When Williams is forced to miss time, this offense tends to struggle mightily. Luckily, Williams has not missed a game this season and his appearance on the injury report could just be rest related once again. Williams also did not practice for all of last week and still played on Sunday. As such, fantasy managers will just need to check back throughout the week and see if there is any news out of San Francisco that suggests Williams will not be able to go this week.

San Francisco 49ers tight end George Kittle (hamstring) intends to play on Sunday, according to Nick Wagoner of ESPN. Kittle was held out of action last weekend and was listed as a limited participant during Wednesday's practice session. The Iowa product has enjoyed another fantastic campaign, averaging an impressive 17.6 PPR points per game. He has found the end zone seven times in eight games and averaged a solid 70.0 receiving yards per game. Fantasy managers should continue monitoring his status throughout the week in case he faces a setback, but he should be expected to return to action and be started in all formats as a high-end TE1.

San Francisco 49ers edge rusher Nick Bosa (hip/oblique) did not practice on Wednesday, according to Matt Barrows of The Athletic. The star edge rusher sustained this injury during last weekend's loss to the Seattle Seahawks. Fantasy managers in IDP formats should continue to monitor his status during Thursday and Friday's practice, as he could be in danger of missing Sunday's tilt against the Green Bay Packers if he cannot return to practice. The former first-round selection has tallied at least one sack in each of the past three games and is averaging 3.6 total tackles per game this season. If Bosa were to sit out this weekend, Yetur Gross-Matos, Sam Okuayinonu, and Robert Beal would likely see an uptick in snaps.

San Francisco 49ers running back Christian McCaffrey (Rest/Achilles) was held out of Wednesday's practice, according to Matt Barrows of The Athletic. McCaffrey has received a heavy workload in both of his games this season and is likely still being eased into a full practice schedule, given the lengthy time he missed earlier in the season. During the past two weeks, McCaffrey tallied at least 20+ touches in each game and saw a season-high 19 carries this past weekend. Fantasy managers should monitor his status throughout the week in case, but he should be expected to return to practice in some capacity on Thursday. The 28-year-old should be viewed as a high-end RB1 for the remainder of the season, given his integral role on one of the best offensive units in the sport.

San Francisco 49ers tight end George Kittle (hamstring) was a limited participant during Wednesday's practice, according to Matt Barrows of The Athletic. The standout tight end was sidelined during last weekend's game due to a hamstring injury. However, seeing him back in practice, albeit in a limited capacity, suggests he could be in line to return to action this weekend to face the Green Bay Packers. Fantasy managers should continue monitoring his status throughout the week in case he faces a setback. Before the injury, the 31-year-old averaged an impressive 74.0 yards and 5.3 receptions per game with six total scores during Weeks 4 through 10. If Kittle can return to action, fantasy managers should view him as a high-end TE1 in all formats this weekend.

San Francisco 49ers quarterback Brock Purdy (shoulder) was limited during Wednesday's practice, according to Matt Barrows of The Athletic. The 24-year-old quarterback suffered an injury in his throwing shoulder during last Sunday's loss to the Seattle Seahawks. Fantasy managers should continue monitoring his progress throughout the week, but seeing him participate in practice early in the week is a promising sign of his availability this coming weekend. Even though Purdy threw for a season-low 159 yards last weekend, fantasy managers should still view him as a solid low-end QB1 heading into Week 12 facing the Green Bay Packers as he has averaged a strong 27.0 PPR points per game during Weeks 6 through 10.

San Francisco 49ers linebacker Dre Greenlaw (Achilles) could have his 21-day practice window opened this week. Greenlaw has been on the injured reserve all season after suffering a torn Achilles during the Super Bowl. It sounds like Greenlaw is close to making it back on the field. The expectation is that Greenlaw will need to practice for a few weeks before getting back into game action. This defensive unit could certainly use Greenlaw's help, but the team isn't going to rush him back to the field. Greenlaw getting back to practice this week would be a huge step forward in his recovery process.

San Francisco 49ers left tackle Trent Williams (ankle) is dealing with some soreness following Sunday's loss to the Seattle Seahawks. Williams was uncertain coming into Sunday's contest due to a lingering ankle issue. However, the All-Pro tackle battled through the pain and suit up over the weekend. He was able to get through the contest, but Williams is now reportedly dealing with soreness in his ankle. This is something the team will likely continue to monitor and might even limit him in practice this week. Williams has played in all 10 games this season and is a significant part to this offense, so hopefully he won't be forced to miss any time.

San Francisco 49ers defensive end Nick Bosa (hips, obliques) will be evaluated throughout the week after being forced from the Week 11 loss to the division-rival Seattle Seahawks on Sunday, according to head coach Kyle Shanahan. Bosa has been dealing with a hip/oblique injury and said he is now dealing with a similar injury on the other side after overcompensating for his previous injury. The Niners defense surely could have used the 27-year-old All-Pro pass-rusher late in Sunday's game against Seattle, and depending on how he recovers this week, they could be without him for a crucial NFC battle with the hosting Green Bay Packers in Week 12. "There's just as good of a chance for him to not play as play," Shanahan said about Bosa playing against Green Bay. It would be a significant downgrade for San Fran's pass rush if Bosa is inactive.

San Francisco 49ers quarterback Brock Purdy (shoulder) is dealing with some right-shoulder soreness on Monday and is considered day-to-day, according to head coach Kyle Shanahan. Purdy might be included on the team's Week 12 injury report but he should ultimately be fine to play this upcoming Sunday on the road at Lambeau Field against the Green Bay Packers. The 24-year-old was without tight end George Kittle (hamstring) in the Week 11 loss to the division-rival Seattle Seahawks and went 21-for-28 for a season-low 159 yards, one touchdown and his eighth interception of the year. His shoulder injury is something to watch throughout the week, but ultimately it shouldn't affect his Week 12 status. Purdy could certainly bounce back as more of a QB1 in fantasy against Green Bay, especially if Kittle is back in action.

San Francisco 49ers tight end George Kittle (hamstring) is expected to return to practice on Wednesday after sitting out the Week 11 divisional loss to the Seattle Seahawks on Sunday due to hamstring irritation that he picked up in the Week 10 win over the Tampa Bay Buccaneers. Head coach Kyle Shanahan said Kittle was "close" to playing on Sunday. Barring a setback once the 31-year-old returns to practice this week, he should be able to return in Week 12 against the Green Bay Packers at Lambeau Field on Sunday. With elevated playing time against Seattle with Kittle out, Eric Saubert failed to take advantage and caught one pass for seven yards. Despite missing two games this year due to injury, Kittle is the TE2 in half-PPR scoring with 43 receptions, 560 yards and a league-leading seven touchdowns. If he's active in Week 12, he's a must-start in fantasy.

San Francisco 49ers rookie wide receiver Ricky Pearsall couldn't get anything going in a Week 11 home loss to the Seattle Seahawks on Sunday. The first-rounder was targeted twice but failed to bring in either pass. It's a bummer for anyone hoping Pearsall could build on his 15.3 half-PPR performance in Week 10, but shouldn't be a surprise. San Francisco's offense was never expected to support three receivers and Jauan Jennings strengthened his claim to the No. 2 -- or even No. 1 -- spot with a second-consecutive 11-target game. Pearsall is a decent stash in case Jennings runs into more injury trouble, but can't be trusted with a fantasy starting slot save for deep-league managers fishing for a touchdown. Pearsall will look to get back onto the stat sheet in Week 12 when he finds himself at Lambeau Field for a showdown with the Packers.

San Francisco 49ers wide receiver Jauan Jennings continued his ascent as a fantasy asset in a Week 11 20-17 home loss to the Seattle Seahawks on Sunday. The former seventh-round pick out of Tennessee caught 10 of 11 targets for 91 yards, including a three-yard touchdown reception to give the 49ers a short-lived lead in the fourth quarter. All four receiving numbers were team highs. Jennings isn't just filling up the stat sheet with empty yards either. He's flashing skill and grit in big spots, which all but solidifies his go-to role in the offense for the rest of the year. With two consecutive 11-target games in the books, it's going to be very hard for fantasy managers to leave Jennings out of lineups in Week 12 when the 49ers travel to Lambeau Field to take on the Packers.

San Francisco 49ers wide receiver Deebo Samuel Sr. laid down a fantasy dud in a 20-17 home loss to the Seattle Seahawks on Sunday. The South Carolina native's seven targets were the second-most on the team -- wideout Jauan Jennings had 11 for the second week in a row -- but Samuel Sr. could only total four catches for 22 yards. He got just one carry which went for a one-yard loss. Samuel Sr.'s fantasy value has rested on his big-play potential more than heavy receiving volume in recent years, but his 5.6 targets per game this season is his lowest since his rookie year in 2019. His yards per reception is still a healthy 14.8 but with only two touchdowns in nine games played, Samuel Sr. hasn't lived up to his high-end WR2 ADP. He is currently the overall WR36 in half-PPR scoring. Fantasy managers will look for Samuel Sr. to get it going next Sunday when the 49ers travel to Green Bay for a Week 12 showdown with the Packers.

San Francisco 49ers running back Christian McCaffrey disappointed again during a 20-17 loss to the Seattle Seahawks in Santa Clara on Sunday. The All-Pro out of Stanford took 19 carries for 79 yards rushing and four catches of five targets for 27 yards in the passing game. It's almost shocking to see McCaffrey fail to reach the end zone for the second consecutive game since returning from his long injury absence. McCaffrey only had three such games total last year (16 starts). It's hard to say whether McCaffrey's conditioning, opponents' defensive game-planning, or personnel changes to San Francisco's offense are to blame. The Niners' rushing attack certainly missed George Kittle (hamstring) today and his knack for springing CMC to long runs. McCaffrey's 4.2 yards per carry against a vulnerable Seattle run defense would have ranked as his fourth-lowest single-game average of 2023. At least McCaffrey appeared to stay healthy from start to finish. McCaffrey's next chance comes against the Packers at Lambeau Field in Week 12.

San Francisco 49ers quarterback Brock Purdy had a better day in fantasy than in real life during a home 20-17 loss to the Seattle Seahawks on Sunday. Purdy hit pregame projections by completing 21 of 28 attempts for 159 yards and a touchdown passing while adding five scrambles for 40 yards and a touchdown on the ground. He was intercepted once. The three-yard scoring pass to wideout Jauan Jennings came in the middle of the fourth quarter to give San Francisco the lead, which was relinquished two drives later with twelve seconds left in regulation. Seattle's reeling defense put up more of a fight than expected and the Niners' offense stalled multiple times by committing their fair share of the team's nine accepted penalties. Purdy's rushing game has been a pleasant surprise, though. His touchdown scramble was his fourth in as many games. He is now in a four-way tie for the fourth-most rushing touchdowns by a quarterback and is ranked 12th in QB rushing yards per game, sandwiched between Denver's Bo Nix and the Giants' Daniel Jones. Purdy will look to get his team back above .500 in Week 12 against the Packers in Green Bay.

Per beat writer Tracy Sandler of FGSN, San Francisco 49ers defensive end Nick Bosa (obliques) is now having trouble with both obliques. Bosa was forced from the team's 20-17 loss to the Seattle Seahawks in Week 11 after injuring his oblique. The 27-year-old came into Sunday's home tilt after missing practice due to a hip/oblique ailment and reported overcompensating on his second sack of quarterback Geno Smith and injuring the other one. Unfortunately, the superstar pass-rusher noted that he's concerned he'll have to miss some time but said, "We're going to see." San Francisco had not let up a touchdown to their division rivals on Sunday until the former first-round pick exited the game. He will almost certainly miss practice again this week, but the 49ers will hope to have him back for their Week 12 road matchup against the Green Bay Packers.

San Francisco 49ers defensive end Nick Bosa (hip) is questionable to return to Sunday's divisional clash with the Seattle Seahawks. The 27-year-old carried a questionable designation heading into this contest. However, he was still a force on the defensive end, totaling four tackles and 1.5 sacks. With the game closer than most anticipated, the Niners would love to see Bosa back on the field. If not, there's a good chance he'll miss practice time leading up to the Week 12 matchup against the Green Bay Packers.

San Francisco 49ers tight end George Kittle (hamstring) is officially deemed inactive for the Week 11 matchup with the Seattle Seahawks. He was already not expected to play, so it doesn't come as too much of a surprise. That leaves Eric Saubert as the next man up. Deebo Samuel Sr., Jauan Jennings, and Christian McCaffrey could also see some added targets.

San Francisco 49ers offensive tackle Trent Williams (ankle) should be ready to suit up for the Week 11 matchup against the Seattle Seahawks. Williams missed practice on Friday due to the ankle issue, but the team believes he should play on Sunday. The 49ers are likely going to wait and see how Williams feels pre-game before making a final decision. The absence of the Pro-Bowl left tackle would be a significant hit to this 49ers offense. Jaylon Moore is listed as second the depth chart, so he'd likely get the start if Williams is unable to play.