Deebo Samuel Sr. Fantasy Stats

San Francisco 49ers wide receiver Deebo Samuel Sr. (hamstring) missed a second straight practice on Friday, according to Harrison Rich of The San Francisco Chronicle. Although the 49ers do not plan to place Samuel on Injured Reserve at this time following his hamstring injury on Sunday in the Week 5 win over the division-rival Seattle Seahawks, the 30-year-old veteran is expected to miss several weeks, including Monday night's clash against the Washington Commanders in Week 6. Fantasy managers should not realistically expect him to make a return until their Week 9 game against the Las Vegas Raiders on Nov. 8 after their bye in Week 8. San Francisco is running out of healthy bodies at the receiver position, with veteran Mike Evans (ribs, Achilles) also hobbled and not practicing yet this week. It is possible that Christian Kirk (calf) makes his return from Injured Reserve this weekend to give the team some reinforcements. Samuel was seeing increased usage in 2026 in his return to the Niners given all their injuries and had 16 catches on 20 targets for 206 yards and three touchdowns before his hamstring injury on Sunday.

San Francisco 49ers veteran wide receiver Deebo Samuel Sr. (hamstring) was not seen in the portion of practice open to the media on Thursday, according to Nick Wagoner of ESPN. Samuel suffered a hamstring injury in the Week 5 win over the division-rival Seattle Seahawks that is expected to sideline him for multiple weeks, so it should not come as a big surprise that he is not practicing on Thursday. The good news for the 30-year-old pass-catcher is that head coach Kyle Shanahan said that the team will hold off on placing Samuel on Injured Reserve due to the team's bye in Week 8. Going on IR would have sidelined him for at least four games. With that said, fantasy managers should still be expecting Samuel to miss several games, so he might not be available again for the 49ers until Week 9. San Francisco's receiving corps is the most banged-up unit around the league, with veteran Mike Evans (Achilles, ribs) holding down the fort while battling through multiple injuries. With Samuel set to miss the Week 6 contest on Monday night against the Washington Commanders, veteran Brandin Cooks and Jacob Cowing will be much more involved, as well as tight end George Kittle.

San Francisco 49ers head coach Kyle Shanahan said on Monday that wide receiver Deebo Samuel Sr. (hamstring) is "going to miss" a couple of weeks with the strained hamstring that he suffered in Sunday's Week 5 win over the division-rival Seattle Seahawks, according to David Lombardi of The San Francisco Standard. Fantasy managers should expect Samuel to miss the next two games against the Washington Commanders and Atlanta Falcons. San Francisco then has their bye in Week 8, so the earliest that Samuel might return could be Nov. 8 at home against the Las Vegas Raiders. It is yet another injury to a key receiver for the 49ers, leaving veterans Mike Evans and Brandin Cooks, who both scored touchdowns on Sunday, and Jacob Cowing as the 49ers' starting receivers going into a Week 6 matchup next Monday night against Washington. The 30-year-old Samuel caught just two passes for 21 yards and carried the ball two times for four yards in Week 5 before leaving in the third quarter and never returning. Samuel has taken on a big role so far in 2025 in his return to the Niners, with their receiving corps so banged up, and he has produced a nice 16-206-3 line for his fantasy managers.

San Francisco 49ers wide receiver Deebo Samuel Sr. (hamstring) is scheduled to undergo an MRI to determine the severity of his injury. Samuel suffered a hamstring injury on a play that resulted in a fumble and was ruled out shortly after he went down. 49ers head coach Kyle Shanahan did not provide an update on the injury's severity in the post-game press conference but said, "I'll probably have one for you guys tomorrow, but I don't think he's coming back this week." In five games, Samuel has 16 catches for 206 yards and three touchdowns, plus 78 yards on the ground. If he misses time, Jacob Cowing and Brandin Cooks should help fill in, but the stars Mike Evans, George Kittle, and Christian McCaffrey will see upticks in usage as well. Fantasy managers should monitor this situation, as Samuel seems likely to miss time with his hamstring injury.

San Francisco 49ers wide receiver Deebo Samuel Sr. (hamstring) has been ruled out for the rest of Sunday's game against the Seattle Seahawks, according to John Dickinson. Samuel looked to be in bad shape when he gingerly limped across the field during the third quarter. He was quickly ruled out for the rest of this game, and we'll see if he's able to suit up against the Washington Commanders next week. He'll finish his day, hauling in two receptions for 21 yards, while rushing the ball twice for an additional four yards on the ground. Mike Evans, Jacob Cowing, and George Kittle will be the primary pass-catchers for the rest of this game.

San Francisco 49ers wide receiver Deebo Samuel Sr. found the end zone again in last week's win over the Denver Broncos, giving him three touchdowns in the first four games of the season. Samuel's versatility has been on display in recent weeks, first being the recipient of a hook-and-ladder toss that he took 80 yards to the house in Week 3, and seeing increased use in the backfield in Week 4, resulting in three carries for 44 rushing yards. In Week 5, the 49ers are facing their stiffest challenge of the season in the Seattle Seahawks. Seattle has held opposing wide receivers to a league-low 395 receiving yards and has given up just 16.8 points per game through four weeks. Samuel will be schemed into the divisional matchup, but he still sits behind Christian McCaffrey, George Kittle, and Mike Evans in the pecking order. He can be started in fantasy football in Week 5 as a WR3/flex option.

San Francisco 49ers wide receiver Deebo Samuel Sr. has wasted no time reacquainting himself with head coach Kyle Shanahan's system in 2026, as evidenced by strong early-season production. The 30-year-old is already up to three touchdowns in San Francisco's first four games, half of his total from a 2025 stint with the Commanders. There may be some inconsistency, since Samuel currently ranks fourth in targets and receptions behind fellow wideout Mike Evans (ribs), tight end George Kittle, and running back Christian McCaffrey. Still, he's involved in the rushing game and is tied with Kittle for the team lead among pass catchers with five red-zone opportunities. Samuel is slated for an imposing Seattle defense in Week 5, though he could get some extra work with Evans banged up a bit.

San Francisco 49ers wide receiver Deebo Samuel Sr. made history in Week 3 with his 80-yard touchdown off a lateral from Mike Evans (ribs). Samuel finished that game without receiving a pass from quarterback Brock Purdy, which gave him the dubious honor of having the most receiving yards without a catch in an NFL game. Samuel wasn't even targeted in the game, but he should be more involved in Week 4 against the Broncos, with Mike Evans (ribs) a game-time decision and Demarcus Robinson (ankle) joining De'Zhaun Stribling (ankle) and Christian Kirk (calf) on injured reserve. On paper, Samuel's matchup is not easy, but last week the Rams were able to exploit Denver's secondary to the tune of 390 passing yards. Samuel is projected as a WR3 in Week 4. His explosive play ability and potential for increased involvement in the 49ers' offense make him worth starting on Sunday.

San Francisco 49ers wide receiver Deebo Samuel Sr. is one of the few players who have stayed healthy within his position group, allowing him to increase his fantasy value as the season goes on. Samuel opened the year in a somewhat crowded receiver room, but he's now one of the only sources of availability with Mike Evans (ribs) in doubt for Week 4 and Demarcus Robinson (ankle), De'Zhaun Stribling (ankle), and Christian Kirk (calf) all on injured reserve. If Evans does miss Week 4, Samuel would step up as the No. 1 receiver with minimal competition alongside him. In that hypothetical scenario, he'd be locked in as a fantasy WR2, which falls in line with his total scoring so far this season. He actually didn't catch a pass last week, but he still managed to post double-digit fantasy points with an 80-yard touchdown off a lateral. A more traditional receiver's role surely awaits Samuel this Sunday, giving him WR2 status with low-end WR1 upside against the Broncos.

San Francisco 49ers wide receiver Deebo Samuel Sr. could see a fair amount of targets in Week 3 against the Arizona Cardinals. The 49ers are dealing with multiple injuries in their wide receiver corps, with Demarcus Robinson (ankle) ruled out, Mike Evans (hip) questionable, rookie De'Zhaun Stribling (ankle) on injured reserve, and Ricky Pearsall (knee) already out for the season. Evans is expected to play on Sunday, but even if he is active, there should be plenty of opportunities for Samuel. Tight end George Kittle and running back Christian McCaffrey will also likely see a fair amount of targets, however. Samuel saw seven targets in Week 1 and four targets in Week 2. He also had one rushing attempt in each of the first two games. Through two games in 2026, Samuel has recorded nine catches for 79 yards and a touchdown, while adding two rushes for 16 yards. He ranks as the No. 24 wide receiver, according to RotoBaller, for Week 3, and is projected to score 9.6 fantasy points. Samuel is worth a look as a WR3 or flex.